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Insulin Resistance and Your Hypothalamus

by | Last updated: Jul 11, 2023 | Hypothalamus, Men's Health, Women's Health | 0 comments

Did you know that hypothalamic dysfunction can cause insulin resistance? Let’s talk about it. 

Insulin resistance occurs when the insulin receptors on your cells are no longer open to accepting insulin.

Insulin resistance is a biological adaptive behavior for hibernating animals and people who live so far from the equator and have little access to food. Therefore, they need to put on a little extra body fat to survive in the winter. Today with food supplies available globally, insulin resistance has become maladaptive and can lead to type two diabetes. 

Insulin resistance is diagnosed when your HBGA1C is above 5.6%, which means that your blood sugars have been high for the past two months. Oftentimes insulin resistance can be seen by the way a person is carrying body fat. The more body fat they have around their middle, the more likely they are to be insulin resistant. That’s because the adipose cells around your waistline never become insulin resistant. They continue to store all the extra carbohydrates that your liver has repackaged into triglycerides for longer term storage which are deposited around your waist. It’s called your insulin later. 

So how is the hypothalamus involved in insulin resistance?

Your hypothalamus controls your glucose metabolism, particularly how much insulin the pancreas produces. As well as cellular metabolism by controlling thyroid hormone production and your circadian rhythm, which controls sleep, energy and general body metabolism.

The optimization of hypothalamus function is crucial in order to resolve insulin resistance. Your hypothalamus produces POMC which controls adrenal function, glucose function, your day/night cycles and also influences thyroid function. Therefore, if your hypothalamus is dysfunctional, you suffer insomnia, have decreased cellular metabolism, and poor glucose tolerance. Your ability to handle stress is affected and high cortisol levels are associated with insulin resistance and diabetes. Also, your liver’s ability to store glycogen and process excess sugar into triglycerides is affected. 

If you want to reverse insulin resistance, trim your waistline back and lower your risk for metabolic diseases including heart disease and diabetes. Above all, you need to optimize your hypothalamus function. 

One of the best ways to optimize your hypothalamus function is supporting it nutraceutically with Genesis Gold®. My patients with insulin resistance who support their hypothalamus with Genesis Gold® have much more success reversing insulin resistance. All with diet, exercise and sleep. More so than those who do not support their hypothalamus nutraceutically.

If you need more information about insulin resistance and your hypothalamus, please join us in free Hormone Reboot Training.


Excerpt from Hypothalamus Handbook

Molecular Mechanisms of Hypothalamic Insulin Resistance; Hiraku Ono;  International Journal of Molecular Sciences; 2019; 20(6): 1317.

Inhibition of Hypothalamic Inflammation Reverses Diet-Induced Insulin Resistance in the Liver; Marciane Milanski;  Ana P. Arruda;  Andressa Coope;  Letícia M. Ignacio-Souza;  Carla E. Nunez;  Erika A. Roman;  Talita Romanatto; Livia B. Pascoal;  Andrea M. Caricilli;  Marcio A. Torsoni;  Patricia O. Prada;  Mario J. Saad;  Licio A. Velloso; Obesity Studies; 2012; vol 61; issue 6

About the Author - Deborah Maragopoulos FNP

Known as the Hormone Queen®️, I’ve made it my mission to help everyone – no matter their age – balance their hormones, and live the energy and joy their DNA and true destiny desires. See more about me my story here…



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