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How is the hypothalamus connected to insulin resistance?

by | Jun 8, 2021 | Hypothalamus | 0 comments

You may be familiar with insulin resistance, but in case you need a refresher, here’s the gist:

Insulin resistance is when your cells do not allow insulin to lock into its receptor site. This increases blood glucose, and can lead to diabetes and metabolic syndrome. Your pancreas has to work harder making more insulin, which leads to type two diabetes.

Insulin resistance is commonly known as pre-diabetes, and is often treated with diet, exercise, and medications. There are also alternative supplements that can help to treat insulin resistance. 

Many are unaware that your hypothalamus actually controls many aspects of your body’s metabolism, including your glucose metabolism, or the way your body deals with sugar. It controls how much sugar your liver will store as glycogen, as well as triglycerides. Excess triglyceride storage leads to fatty liver. Your hypothalamus also controls your adrenal glands.  Excess cortisol, which is caused by too much stress over long periods of time, has been indicated to increase in risk of insulin resistance. 

What ends up happening is this: A dysfunctional hypothalamic-pituitary-adrenal axis creates miscommunication between your hypothalamus and adrenal glands, leading to an exaggerated stress response and too much cortisol production. Your hypothalamus controls your metabolism, or how fast you burn energy, and it is glucose that is burned as energy. So if your metabolism is slower, then you’re not going to be utilizing your glucose appropriately. 

The main way that the hypothalamus is connected to insulin resistance is its production of a hormone called proopiomelanocortin or POMC. POMC is a pre-hormone that gets broken into a cortisol-releasing factor that controls adrenal function, which then controls your stress response and cortisol production. 

POMC is broken into a thyroid-releasing factor, which controls thyroid function, and in turn, your metabolism. This then gets broken into a glucose-releasing factor, which controls your glucose metabolism by your liver and cells. POMC also gets broken down into melanocyte-stimulating hormones, which controls your day/night cycles and your metabolic rate. 

POMC controls so many aspects of how glucose is utilized in the body. When your body has too much sugar floating around, and it cannot use it for energy, insulin resistance is the natural reaction to prevent cells in organs like your heart from growing too big, because they can’t use it for energy, and have no way to store the sugar. If your hypothalamus perceives that you’re consuming more sugar than you use for energy, it will slow your metabolism down, which will increase the risk of insulin resistance. 

Insulin resistance is the first step towards diabetes, and a common issue for women with PCOS (polycystic ovary syndrome.) Insulin resistance is treated at the endpoint, in what we call downstream medicine. Downstream medicine is treating the symptoms, and not the cause of the symptoms. In contrast, upstream medicine is looking at what’s causing the symptoms.

Usually, it’s an imbalanced hypothalamus that  causes many of these problems. Supporting your hypothalamus with Genesis Gold® helps reprogram the way your body uses glucose and will resensitize your cells to insulin, whether you have type two diabetes, polycystic ovary syndrome, or pre diabetes. Fortunately, insulin resistance can be corrected through a special diet, consistent exercise, and supporting your hypothalamus. 

If you may be suffering from insulin resistance, you don’t have to go through it alone. Why don’t you join us in our Hormone Support Group, which you can get access to through our Free Hormone Reboot Training. I hope you’ll join us.

About the Author - Deborah Maragopolous FNP

Known as the Hormone Queen®️, I’ve made it my mission to help everyone – no matter their age – balance their hormones, and live the energy and joy their DNA and true destiny desires. See more about me my story here…



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Deborah Maragopoulos FNP - The Hormone Queen

Deborah Maragopoulos FNP
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