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Is Too Much Estrogen Really Causing Your Uterine Bleeding?

by | Last updated: Oct 31, 2024 | Menopause, Women's Health | 2 comments

Let’s talk about the estradiol side effect of uterine bleeding. 

Estrogen

Estrogen is a growth-promoting hormone, and one of its jobs is to make the endometrial lining of the uterus thicker. If estrogen is unopposed, meaning you don’t have enough progesterone on board, your endometrial lining will become too thick, and start to slough off causing uterine bleeding. 

Uterine bleeding can happen in the middle of the cycle if estrogen and progesterone are out of balance. It can happen in menopausal women when they’re not taking enough progesterone to counterbalance how much estrogen they’re taking.

Uterine bleeding can range from spotting to heavy hemorrhagic bleeding. If you have unusual uterine bleeding, a pelvic ultrasound can help provide answers. Definitely for postmenopausal women, if you have uterine bleeding after not bleeding for at least 13 months, you need a pelvic ultrasound to measure the endometrial lining. 

For postmenopausal women, the endometrial lining should be no thicker than four millimeters, otherwise there might be a chance of endometrial hyperplasia. If the endometrial lining is very thick on pelvic ultrasound, you may need an endometrial biopsy in which a small amount of tissue is extracted from the endometrium through the cervix during the pelvic exam. The tissue is sent to pathology which looks for abnormal cells including cancer. 

Prevent Uterine Bleeding

To prevent uterine bleeding, postmenopausal women need to take at least 100 milligrams of progesterone per one milligram of estradiol.

Postmenopausal women, who cannot take enough progesterone to counterbalance their estrogen, also have the option of using a progestin-impregnated intrauterine device to dry up the lining of the uterus and prevent endometrial hyperplasia and uterine bleeding. 

For irregular mid-cycle bleeding in pre-menopausal women, taking progesterone up to 200 milligrams twice a day in the second half of their cycle can help regulate their cycles. 

I recommend Gen-Pro™ transdermal micronized progesterone cream. 

If you have any questions about uterine bleeding, Please join us in Hormone Reboot Training.

Hormone Reboot Training

Resources:

https://pubmed.ncbi.nlm.nih.gov/32893694

About the Author - Deborah Maragopoulos FNP

Known as the Hormone Queen®️, I’ve made it my mission to help everyone – no matter their age – balance their hormones, and live the energy and joy their DNA and true destiny desires. See more about me my story here…

     

2 Comments

  1. Beza Daniel

    Hi.
    I’m on BHRT with testosterone. I take progesterone 200mg troche. I can’t handle the pill form. I would like to use the transdermal form. I’m having bleeding for 2 weeks now. I’m not sure if the troche is giving me enough progesterone. Would you help me understand? Thank you!

    Reply
    • Deborah Maragopoulos FNP

      Progesterone helps to counterbalance estrogen.

      Keeping your progesterone in balance is key, especially during times of stress, because progesterone is the precursor to your adrenal stress hormones. When you’re under high levels of stress, progesterone will be robbed from your ovaries to make stress hormones.

      If you’re pre-menopausal, low levels of progesterone can cause irregular periods, no periods at all, increased PMS, and even infertility. Low progesterone can cause very heavy bleeding because of the unopposed estrogen.

      If you’re menopausal, not having enough progesterone in your system causes stress to wreak way more havoc in your internal organs, causing inflammation. Low progesterone affects your brain chemistry leading to anxiety, poor sleep, and brain fog. Most women need help navigating the change. Why don’t you grab your Menopause Action Plan Guide here: https://genesisgold.com/map-guide/

      Reply

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