What Causes PCOS? | How To Avoid PCOS Naturally

by Deborah Maragopoulos FNP | Feb 15, 2019 | PCOS | 0 comments

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Ever wonder what might be the cause of your PCOS? Well, we are going to go over the three main causes so that you understand a little bit better, in our ongoing blog topic: PCOS.  Primarily, it is important to understand the genetics of PCOS. If you have a mother, an aunt, a grandmother, even a sister that has PCOS, you are more likely to develop PCOS. PCOS is basically a genetic factor very similar to diabetes and heart disease.

Hormone Healing Tip 1: Genetics can Indicate PCOS

Those same genes that run cardiovascular disease, insulin resistance, and diabetes affect PCOS. Because those genes can be affected by lifestyle, diet, exercise, or supplementation, you can actually change the way the genetics are expressed. Meaning that just because your mother has PCOS does not necessarily mean you have to have PCOS. Your DNA, or your genetics, is really like playing a hand of cards. You are dealt out a certain variety of genes, or cards. How you play those cards determines whether or not you are going to stay in the game.

So you may have the PCOS tendency in your genetics, but if you live a lifestyle that does not promote inflammation, you live a lifestyle that is stress-free, you live a lifestyle that promotes healthy hormones, then you will not develop PCOS. So, the genetics of PCOS is just one of three different causes of PCOS.

Hormone Healing Tip 2: Stress Triggers PCOS

Number two is stress triggers PCOS. If you have the DNA for PCOS and you are under very high levels of stress, because the adrenal glands are a huge issue in PCOS, producing too much DHEA or the androgenic adrenal hormone. High-stress levels raise that hormone level up and will actually trigger PCOS. PCOS is irregular cycles. You end up having hirsutism or hairiness that is caused by the high levels of DHEA, which converts over to male hormone, or testosterone. You can have increased acne and increased weight gain around your middle. That is all caused by high-stress hormones.

Because stress triggers PCOS, you can actually help to reduce stress and actually reverse PCOS symptoms and actually reverse PCOS by reducing your stress. Meditation and breathing exercises can actually help reduce the stress and reduce the symptoms of PCOS.

Hormone Healing Tip 3: Diet Contributes to PCOS

Number three, your diet contributes to PCOS. Because PCOS genetically is similar to diabetes and insulin resistance, those females, who actually eat very high levels of sugar and starches and they do not exercise enough to burn that off, can develop PCOS. They will develop the insulin resistance that we see in PCOS, where their cell receptors are not receptive to insulin in sugar, and that forces more and more of that insulin in sugar to go to the fat cells around their middle rather than using it as energy.

So reducing your carbohydrates in your diet, especially those starchy carbs like pastas and breads and the sugars, makes a huge difference in whether or not you are going to develop PCOS. So, three things, genetics, stress, and diet, are all potential PCOS causes, and you can prevent PCOS by actually reducing your stress and eating a healthy insulin-resistant type diet. Thank you.

Frequently Asked Questions:

Can your hypothalamus cause weight gain?

Yes. The hypothalamus is the master regulator of metabolism, controlling how your body stores and burns energy through its signaling to the thyroid, adrenals, and pancreas. When the hypothalamus becomes dysregulated by chronic stress, poor sleep, inflammation, or blood sugar instability, it defends a higher weight "set point" — causing the body to hold onto fat regardless of diet or exercise. This makes hypothalamic dysfunction an upstream root cause of stubborn weight gain.


What is a weight set point and why won't mine move?

A weight set point is the body weight your hypothalamus works to defend, calibrated over time by stress, sleep, hormones, and inflammation. When you diet, the hypothalamus perceives scarcity and responds by slowing metabolism, increasing hunger hormones, and suppressing satiety signals to return you to that set point. This is why most people regain lost weight within two to five years of conventional dieting — the set point itself was never recalibrated, only temporarily overridden.


Why do I gain weight under stress even when I'm not eating more?

Chronic stress raises cortisol, which disrupts blood sugar regulation, promotes abdominal fat storage, and signals the hypothalamus that the body is under threat. In survival mode, the hypothalamus defends fat stores and slows metabolism — so weight can increase even without any change in calorie intake. The stress chemistry, not the food, is driving the weight gain, which is why stress reduction is essential to any lasting metabolic reset.


Why do I regain weight after stopping GLP-1 medications?

GLP-1 medications work peripherally on appetite and gastric signaling, but they do not address the underlying hypothalamic dysregulation that sets your defended weight. Because the hypothalamic set point is never recalibrated, the body resumes defending its original weight once the medication stops — leading to significant regain. Long-term success requires restoring hypothalamic regulation so the set point itself lowers, rather than relying on appetite suppression alone.


How long does it take to reset your metabolism?

Genuine metabolic recalibration takes a minimum of 90 days, because the hypothalamus needs consistent signals of safety and sufficiency before it will lower its defended set point. This differs from a diet, which produces temporary suppression the body quickly corrects. A 90-day reset typically moves through three phases: stabilizing stress chemistry (days 1–30), rebuilding metabolic efficiency (days 31–60), and lowering the weight set point (days 61–90).


Why does my thyroid feel slow even though my labs are "normal"?

Under chronic stress, the body converts thyroid hormone into reverse T3, which blocks active thyroid receptors and slows metabolism at the cellular level — even when standard lab values appear normal. This means you can experience genuine symptoms of slow metabolism, such as fatigue, cold intolerance, and brain fog, while your thyroid panel looks unremarkable. Addressing the upstream hypothalamic and stress signaling often improves thyroid conversion and symptoms.


Is stubborn weight gain a willpower problem?

No. Stubborn weight gain is a signaling problem, not a willpower problem. The hypothalamus governs weight through survival mechanisms that operate below conscious control — defending its set point by slowing metabolism and increasing hunger when it perceives threat. No amount of discipline can override this system; lasting change comes from restoring hypothalamic regulation through reduced stress, balanced blood sugar, restorative sleep, and targeted nutritional support.

About the Author - Deborah Maragopoulos FNP

Known as the Hormone Queen®️, I’ve made it my mission to help everyone - no matter their age - balance their hormones, and live the energy and joy their DNA and true destiny desires. See more about me my story here...

     

Last Updated: April 6, 2022

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