So how do thyroid hormone and testosterone affect one another?
Let’s talk about it.
All hormones are interconnected including thyroid and testosterone. Testosterone has been shown to affect thyroid hormone production and function.
Studies show that exogenous testosterone (testosterone replacement therapy) changes thyroid hormone production, especially autoimmune thyroiditis.
Exogenous testosterone may have a protective effect on the thyroid particularly against autoimmunity.
We also know that the thyroid hormones directly impact the metabolism of sex hormones including testosterone. Hormone function changes, either increased or decreased, can disrupt optimal testosterone levels. Hypothyroidism or underactive thyroid is associated with lower testosterone production.
The effect on thyroid hormone by testosterone has been studied in trans men. When given exogenous testosterone to trans men their thyroid actually increases in size. It’s been postulated that male metabolism being more active than female metabolism requires a larger thyroid gland. Thus testosterone increases in puberty increases the thyroid volume and its hormone production.
Optimizing hypothalamus function is critical if you’re considering testosterone replacement therapy. First to minimize effects on other glands including the thyroid and to improve testosterone metabolism. My patients who use Genesis Gold® daily can use less testosterone and have more oil hormone production.
If you have questions about testosterone and thyroid function, please join us on Hormone Reboot Training.

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