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Is PCOS an Autoimmune Disease?

by | Last updated: Jan 18, 2023 | Blog, PCOS | 0 comments

Polycystic ovary syndrome, or PCOS, is a condition in women characterized by chronic high testosterone levels and an anovulatory state, meaning not ovulating regularly. The imbalance of estrogen to progesterone in people with PCOS seems to stimulate the hyper-reaction of the immune system, and may contribute to autoimmune conditions. 

In women with PCOS, low levels of progesterone overstimulate the immune system. Which may lead to the production of auto-antibodies, which attack your tissues. An autoimmune disease is any condition in which your immune system produces antibodies against you.

Currently, the medical field does not consider PCOS an autoimmune disorder, but it is associated with many autoimmune diseases.

PCOS causes inflammation and hyperstimulation of your immune system. This can cause tissue destruction. When cells are destroyed, ANA (anti-nuclear antibodies) are produced. The presence of ANA is the hallmark of autoimmune diseases, and often we see ANA in patients with PCOS. We also see high levels of other autoimmune antibodies in people with PCOS. Including autoimmune thyroid antibodies, thyroid peroxidase antibodies, anti-sperm antibodies, and anti-thyroid globulin, which are anti-islet cell antibodies that attack the beta cells of the pancreas.

The most classic autoimmune condition that is associated with PCOS is thyroiditis or low thyroid function with autoimmune antibodies.

However, hyperthyroidism, which means high thyroid function with autoimmune antibodies, can also occur. 

Since it’s a metabolic syndrome with high inflammatory markers, PCOS can contribute to metabolic issues leading to insulin resistance. As well as central obesity, high blood pressure, and high cholesterol. These inflammatory, metabolic reactions can interfere with normal immune functioning. 

Most of the issues associated with polycystic ovary syndrome can be linked to the hypothalamus.

The hypothalamus controls your reproductive hormones. So the miscommunication between the hypothalamus, pituitary gland, and ovaries is part of the issue for people with PCOS. 

Your hypothalamus controls your immune system as well. And in patients with autoimmune conditions, their hypothalamus is often dysregulated. Supporting your hypothalamus with Genesis Gold, especially if you have PCOS, can help to reverse polycystic ovary syndrome and reduce autoimmune tendencies. 

It is not easy living with polycystic ovary syndrome or autoimmune disorders, but thankfully, there are many ways you can reduce the painful or burdensome symptoms that are associated with these conditions. If you have any questions about polycystic ovary syndrome or autoimmunity, join me in our Hormone Support Group, where you’ll get access to our free Hormone Reboot Training. 

About the Author - Deborah Maragopoulos FNP

Known as the Hormone Queen®️, I’ve made it my mission to help everyone – no matter their age – balance their hormones, and live the energy and joy their DNA and true destiny desires. See more about me my story here…



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